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Prof. Dr. István Szikora

Continuation Committee

ESMINT President 2014-2016

Istvan Szikora M.D., Ph.D.
Department of Neurointerventions, National Institute Mental Health, Neurology and
Neurosurgery
Section of Neurointerventions, Department of Neurosurgery, Semmelweis University Medical School
Budapest, Hungary

Istvan Szikora belongs to the ESMINT ExCom.

Education

1970-1977: Semmelweis University Medical School, Budapest MD, cum laude

1981: Board exam in Anaesthesiology and Intensive Care

1988: Board exam in Radiology

1999: Semmelweis University Medical School, Budapest Ph.D., Medical Radiology

2001: Board exam in Neuroradiology

2007: Semmelweis University Medical School, Budapest, Habilitation

Employment

1991 – 1994: Research Assistant Professor, Department of Neurosurgery, State University of New York at Buffalo (SUNYAB), Buffalo, NY, USA

2005 – 2007: Deputy Director, General, National Institute of Neurosciences (NIN)

2010 – 2022: Head, Department of Neurointerventions, National Institute of Neurosciences (NIN) Deputy Director, Research and Science, National Institute of Neurosciences (NIN)

2017 – 2022: Chairman, Department Section of Neurointerventions, Semmelweis University Medical School, Budapest

2022 – present: Senior Consultant, Department of Neurointerventions, National Institute Mental Health, Neurology and Neurosurgery

Professional Activities and Research Projects

  • Flow alteration in the treatment of intracranial aneurysms. Experimental studies (SUNYAB)
  • Liquid polymers in the experimental treatment of aneurysms (SUNYAB)
  • Experimental induction of aneurysms using Elastase (SUNYAB)
  • Application of intravascular ultrasound in flow stuides of experimental aneurysms (SUNYAB)
  • Introduction of endovascular treatment for intracranial vascular disease in Hungary (NIN)
  • Endovascuar treatment of intracranial aneurysms (NIN, supported by ETT 1993, OTKA 2000)
  • Biomechanical modelling of intracranial aneurysm rupture (NIN, supported by ETT, 2003)
  • Flow simulation of intracranial aneuryms (NIN, supported by OTKA, 2004)
  • Endovascular treatment of intracranial aneurysms using polymer coated microcoils (NIN, 2005)
  • Endovascular treatment of intracranial aneurysms using inravascular stents (NIN, 2006)
  • Effect of perianeurysmal environment on intraaneruysmal flow (NIN, supported by OTKA, 2007 -)

Scientific Achievements

  • Computerised study of hemodynamics and flow modifying treatment of intracranial aneurymsms KTIA_NAP_13-1-2013-
    0001 Hungarian National Brain Research Program
  • Role of helical and chaotic flows in the development and treatment of intracranial aneurysms: Computational Fluid Dynamics and mechanical studies. 2017-1.2.1-NKP-
    2017-00002, Hungarian National Brain Research Program 2.0
  • Book chapters: 26
  • Scientific publications in international journals: 213
  • Independent citations: 9187
  • Hirsch index: 37
  • Cumulative impact factor of publications: 376,017

Professional affiliations

President:

  • Hungarian Society of Neuroradiology (HSNR)
  • European Board of Neurointerventions (EBNI)
  • European Foundation of Minimally Invasive Therapy (EFMINT)

Executive Committee member:

  • Hungarian Society of Neurosurgery
  • Hungarian Society of Neuroradiology
  • Hungarian Stroke Society
  • European Society of Minimally Invasive Neurological Therapy (ESMINT)

Honorary Member:

  • European Society of Minimally Invasive Neurological Therapy

Full Member:

  • European Society of Neuroradiology
  • American Society of Neuroradiology
  • World Federation of Interventional and Therapeutic Neuroradiology
  • American Society of Interventional and Therapeutic Neuroradiology
  • Hungarian Society of Radiology
  • National Board of Radiology
  • National Board of Neurosurgery

International Congresses:

  • President, 5th Congress of ESMINT, September, 2013, Nice, France
  • President, 14th Congress of WFITN, October, 16-19, 2017, Budapest

Primary investigator in scientific grants

  • National Science and Research Fund (OTKA) T32770, 2000-2003: Endovascular treatment of intracranial aneurysms
  • National Science and Research Fund (OTKA) T047150 OPR, 2004-2006: Flow simulation of intracranial aneurysms
  • National Science and Research Fund (OTKA) OTKA 73773: Impact of peri-aneurysmal environment on intra-aneurysmal flow dynamics and their effect on the natural history of the disease

Clinical Research Experience:

  • Pipeline for Uncoilable or Failed Aneurysms (PUFS): 2008-2014
    • Sponsor: Chestnut Medical Technologis Inc., Protocol No. CLP-005.A
  • WEB Clinical Assesement of Intrasaccular Aneuryms Therapy – Basilar Apex
    (WEBCAST-B): 2011-

    • Sponsor: Sequent Medical Inc., Protocol No. Sequent 11-001
  • WEB Clinical Assesement of Intrasaccular Aneuryms Therapy (WEBCAST-2):
    2014 –

    • Sponsor: Sequent Medical Inc., Protocol No. Sequent 11-001
  • The WEB Intrasaccular Therapy Study (WEB-IT): 2015-
    • Sponsor: Sequent Medical Inc., Protocol No. CP13-001
    • Audited by the US FDA Jan, 22-25, 2018. 05. 24.
  • TREVO Registry: 2014-2017
    • Sponsor: Stryker Neurovascular, Protocol No. CDM10000023
  • Pipeline Flex with SHIELD Technology Emblization – An International Multicenter Observational Post Market Study of Treated Intracranial Aneurymsm (SHIELD) Registry: 2017 – 2019
    • Sponsor: Medtronic Neurovascular, Protocol No. NV-PED-010
  • NeuroVascular Product Surveillance (INSPIRE Registry )
    • Sponsor: Medtronic Neurovascular
    • Ongoing
  • ClinicalStudyoftheContourNeurovascularSystemTM,ProtocolNo.:DNX065-11 o
    • Sponsor:CerusEndovascularLimited
  • Evaluation of the Thrombex Retriever in the Ravascularization of Patiens with Acute Ischemic Stroke Due to LVO.
    • Sponsor: ThrombeX Medical, Protocol No. CLP T0069