On Monday, 13 February 2023 from 5 PM – 6 PM CET, we will host an ESMINT Webinar on The value of intravenous thrombolysis in patients with LVO anterior circulation stroke: An update on clinical implications from recent large trials.
The webinar will be moderated by Dr. Jan-Hendrik Buhk (Hamburg, Germany). The speakers of the ESMINT webinar are Prof. Urs Fischer and Prof. Jan Gralla (both Berne, Switzerland).
This is a special ESMINT Webinar and is free of charge.
What is the webinar about?
Recent RCTs have evaluated the effect of intravenous thrombolysis in mothership patients with large artery stroke. This webinar summarizes the results of the individual trials and an individual participant meta-analysis (IRIS), and elucidates the consequences in clinical practice.
Key message
In the pooled analysis of six stroke trials, intravenous thrombolysis shows a limited effect on top of thrombectomy in large artery anterior circulation stroke. Thrombectomy is the backbone of treatment in these patients and thrombolysis should not postpone or omit thrombectomy.
The trials open room for improvement in the future, e.g. timing of drug application and thrombolytics in more peripheral occlusions.
Your learning objectives
- Historical perspective of stroke trials and recent results
- Effect size of IVT in the bringing concept in large artery anterior circulation stroke
- Novel concepts of thrombolytic drug application in future trials
About the speakers
Urs Fischer is a clinical neurologist, who trained in Bern/Switzerland and Oxford/UK. He is the Chair and Director of the Department of Neurology at the University Hospital of Basel, Switzerland. His main research interest involves diagnosis, management, treatment and outcome of patients with acute ischaemic and haemorrhagic stroke. He is principal investigator of several international multicenter academic stroke trials (e.g. global co-PI of the SWIFT Direct Trial and a collaborator of the IRIS pooled analysis).
Jan Gralla is a qualified diagnostic and interventional neuroradiologist who received training in Erlangen/Germany, Oxford/UK and Bern/Switzerland. He is the Chair and Director of the Department of Neuroradiology at the Inselspital, University of Berne, Switzerland. His main research focus is the treatment of acute ischemic and he is involved in various project e.g. global co-PI of the SWIFT Direct Trial and a collaborator of the IRIS pooled analysis.
What to expect?
This ESMINT webinar provides you with the opportunity to meet experts, who will share their experience, practice, and way of thinking regarding everyday challenges in the field of neurointerventions with you.
The webinar will be an interactive live transmission. All participants will be able to ask questions via the online chat function.